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Macintosh Picture Format  |  1995-08-22  |  315KB  |  449x709  |  8-bit (48 colors)
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OCR: AUTOANT GENS IN AUTOIMMUNE THYROID DISEASE thyroglobulin thyroid TSH-R peroxidase protein iodinatec haemoprotein G-binding glycoprotein enzyme protein- -linked receptor glycosylated function biosynthetic catalyses iodination receptor for TSH precursor and coupling of TE and tyrosne to yield T3 andf T4 thyroid ocation folfcular lumen membrane -bouna membrane-bound cell surface (apical) cell surface (basal) exo- fendocytotic vesicles molecular weight 660.000 105,000 86.000 110.000 amino acids 2.748 TPO-1 1.933 764 TPO-2876 (excludes 20 atematively amino-acid T2u3s spliced products sequence) region extracelular 842(TPO-I) 418 transmembrane 265 transmembrane domains) intracellular chromosome location homologies acetyicholinesterase mycloperoxidasc luteinising receptors Hormonefhumani chorionic ...